Medtronic makes a first step towards “closed loop” with “low glucose suspend” feature

Medtronic just published results from their ASPIRE study showing decreased time in hypoglycemia for patients using their new “low glucose suspend” feature.  The new system will automatically and temporarily suspend insulin delivery if the patient’s glucose falls below a set threshold value.  In this case, the threshold of <70 mg/dl was used.

Automatic prevention of hypoglycemia is a big step forward in assuring the safety of patients with type 1 diabetes.  What will be an interesting next step will be to see if this data is reproducible in a “normal,” home environment, since this study was done by inducing hypoglycemia through exercise in a research setting.  Though we may or may not see major improvements in long-term clinical outcomes with this new technology, it seems like it may start to reduce the need for waking up with hypoglycemia and having a snack at 4am, and it seems like a step closer to realizing a “closed loop.”

I know that there are a number of patients who use Medtronic pumps and Dexcom sensors because they find the Dexcom sensor more comfortable.   This new feature requires use of both the Medtronic pump and Medtronic sensor in order to create the first step towards a closed-loop system.  I wonder whether this new feature will convince at least a few patients to switch to using a Medtronic sensor.

I’d be curious to hear comments from any patients who are in this situation and what your thoughts are.

Graph below taken from the Diabetes Technology and Therapeutics publication showing glucose values from patients with and without the low glucose suspend feature.

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About Aaron Neinstein, MD
I'm an Assistant Professor in Endocrinology and Director of Clinical Informatics at the University of California, San Francisco.

One Response to Medtronic makes a first step towards “closed loop” with “low glucose suspend” feature

  1. divabetic913 says:

    Hi!
    I’m a Type 1 diabetic, and I actually wrote a post today about my first experience trying CGM. I recently spoke to a Dexcom representative about trying it out. When I tried CGM it was so uncomfortable and invasive. I could feel the cannula under my skin. Albeit, if you read my post, the majority of the reason that I ended up having a panic attack and vomiting with CGM was for other reasons…I honestly don’t feel that even if CGM came with glucose suspension that I would be able to tolerate wearing it. I know a few other diabetics that tried out CGM and ended up ripping it out after a few hours to discomfort. I feel like the length and width of the of the Medtronic CGM is just unnecessarily large when you consider the other working models on the market.

    Like

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